Lactulose hydrogen breath test has been used for measurement of orocecal transit time (OCTT) because of its non-invasiveness and simplicity. Recently, the lack of reproducibility of OCTT which measured by hydrogen breath test using water-diluted
lactulose resulted in the need to develop a new semisolid or solid meal combined lacturlose hydrogen breath test. We measured OCTT in 47 normal subjects(male 17, female 30, age 24-69 years, average 35.5 years) after ingestion of semisolid meal
including
potato soup and lactulose syrup 20g. OCTT was defined as teh time from test meal ingestion to a sustained increase of more than 10ppm above the baseline in end-expiratory hydrogen concentration with 10 minutes interval for 3 hours. OCTT was
79.2±11.9(mean±SD) minutes in male, 81.5±15.2 minutes in female, and average 81.9±13.3 minutes. Although there was no significant difference according to sex, OCTT in sixth and seventh decades were delayed compared to third decades(P<0.05).
These
results will be useful for comparison of OCTT in different group of patients.(Korean J Gastroentero,l 1994 ; 26 : 619-624)
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